Xeomin botulinum toxin
Relaxes the muscles that crease the forehead, brows and eyes so etched lines can gradually soften.
Wrinkles & Volume Loss
Deep Wrinkle Treatment in Gangnam, Seoul
A structured plan for established wrinkles at Nest Clinic — our women doctors combine botulinum toxin, carefully placed fillers and collagen-building lifting devices to soften deep creases while keeping your expression natural.
2–12 wks
for gradual, layered softening
A
How do you get rid of deep wrinkles on the face?
Deep wrinkles are rarely solved by one treatment, because they combine muscle movement, volume loss and weakened collagen. Doctors usually relax overactive muscles with botulinum toxin, support folds with hyaluronic acid filler, and rebuild collagen with devices such as Ulthera, Thermage FLX or Sculptra. Filler effects are immediate, toxin takes 1–2 weeks and collagen improvement builds over 2–3 months. Deep wrinkles soften rather than disappear, and results vary.
- Sessions
- 1–3 depending on the combination
- Interval
- Toxin every 3–4 months; devices yearly
- Downtime
- Mild swelling or bruising for 2–5 days
- Treatment time
- About 30–60 minutes
- Results last
- Around 4–18 months, by treatment
- Reversibility
- HA filler can be dissolved if needed
Understanding deep wrinkles
Why some lines become etched
Deep wrinkles are static creases that remain visible even when the face is at rest. They form over years as collagen and elastin decline, fat pads thin or descend, and repeated muscle movement folds the same skin again and again. Sun exposure, smoking and genetics speed this up.
They commonly appear as forehead lines, frown lines between the brows, nasolabial folds and marionette lines. Each area has a different cause, so each needs a slightly different approach.
Signs of deep wrinkles
- Lines remain visible with a relaxed face
- Creases do not fade after moisturiser or rest
- Folds that cast a shadow under overhead light
- Lines accompanied by sagging or volume loss
- Previous skincare alone has made little difference
Deep folds are often linked to sagging skin
— lifting the tissue can soften a fold more naturally than filling it alone.
Our approach
Treating every layer
We match each wrinkle to its main cause — movement, volume or laxity — and combine treatments accordingly.
Hyaluronic acid fillers
Juvéderm, Restylane or Belotero support deep folds immediately. Soft, fine fillers are used for etched lines in thin skin.
Sculptra collagen stimulation
Poly-L-lactic acid gradually rebuilds collagen and volume over several sessions — see our Sculptra page.
Ulthera & Thermage FLX
Focused ultrasound and radiofrequency lift and tighten lax tissue that deepens folds, with results developing over 2–3 months.
Potenza & CO2 fractional
Microneedling RF or fractional laser resurfaces the skin to improve deep, textured creases.
Rejuran & skin boosters
Improve skin thickness and elasticity so results from other treatments look smoother and last longer.
What to expect
Softer folds, natural expression
Drag the handle to compare. Deep creases ease in stages as muscles relax, volume is supported and new collagen forms.
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Before
After 12 wks
Illustration for explanation only — not a patient photograph. Individual results vary; real case photos are shown during your consultation.
Is it right for you?
Good candidates
- Static lines on the forehead, brows or around the mouth
- Folds that are accompanied by volume loss or sagging
- People wanting improvement without surgery
- Those who can return for a review at 2 weeks, or continue care at home
- Adults in good general health with realistic expectations
Very deep folds with significant skin excess may be better addressed surgically — we will tell you honestly if that is the case.
Safety first
Possible side effects
Common, temporary effects include swelling, redness, tenderness and bruising at injection or treatment sites. Botulinum toxin can occasionally cause temporary brow or eyelid heaviness or asymmetry. Fillers carry uncommon risks of lumps, infection and, rarely, vascular occlusion, which can affect skin or vision.
To reduce risk our doctors use detailed facial anatomy, cannulas where suitable, slow low-pressure injection and conservative volumes, and keep hyaluronidase on hand to dissolve hyaluronic acid filler if needed.
We do not inject during pregnancy or breastfeeding, over active infection, or for patients with certain neuromuscular or autoimmune conditions.
Your visit
How treatment works at Nest Clinic
Facial assessment
Your doctor maps movement, volume and laxity.
Combination plan
Toxin, filler and devices chosen and sequenced.
Comfort
Numbing cream or ice before treatment.
Treatment
Precise injections or device session, 30–60 minutes.
Review
Check at 2 weeks or by photo if you have flown home.
Medical reviewer · Chief Medical Doctor
Dr. Kyung-yeon Lee
Dr. Lee trained at Seoul National University College of Medicine (M.S.) and completed residency at Seoul National University Hospital. Before joining Nest Clinic she was director at VS Line Clinic in Apgujeong. Nest Clinic is led entirely by women doctors, with one-to-one consultations rather than high-volume treatment.
Seoul National Univ. College of Medicine
Korean Society for Aesthetic Laser Surgery
Korean Academy of Facial Filler
Key Doctor · Jetema e.p.t.q.
This page was medically reviewed by Dr. Kyung-yeon Lee in October 2026. It is for general information and does not replace an in-person diagnosis.
FAQ
Deep Wrinkles questions, answered
Can deep wrinkles be removed permanently?
No treatment stops ageing, so results are not permanent. Deep wrinkles can be visibly softened, and regular maintenance keeps them looking smoother over time.
Is filler or Botox better for deep wrinkles?
They do different jobs. Botulinum toxin relaxes the muscles that fold the skin, while filler supports lost volume. Lines on the upper face often respond to toxin; folds on the lower face usually need filler or lifting. Many plans use both.
How long is the recovery?
Most patients return to normal activities the same day. Swelling or bruising, if any, usually settles within 2–5 days. Lifting devices typically leave only mild redness.
I'm visiting Seoul for one week. What can I do?
A week is enough for toxin, filler and a lifting device session. We suggest treating early in your stay so we can review you before you fly.
Does treatment hurt?
Numbing cream and fillers containing lidocaine keep injections comfortable. Ulthera can feel warm or briefly sharp, and settings are adjusted to your comfort.
What if I only have early lines?
Shallow lines often need lighter treatment — see our fine line treatment
page.
Related treatments
Explore wrinkle care
Consultation
Plan your wrinkle treatment
Send a photo on WhatsApp for a first opinion in English, then book a facial assessment with our doctors.
Nest Clinic Gangnam · 4F–5F Seocho Building, 453 Gangnam-daero, Seocho-gu, Seoul
Sinnonhyeon Station Exit 7 · Gangnam Station Exit 10
Mon–Fri 10:00–20:00 · Sat 10:00–17:00 · Sun closed
Results differ from person to person. All medical procedures carry potential risks and side effects; a doctor will explain them before treatment. Information on this page is educational and not a substitute for a personal medical consultation.
