Xeomin botulinum toxin
Precise injections into the frowning muscles soften lines and help prevent them deepening.
Wrinkles & Volume Loss
Glabellar Line Treatment in Gangnam, Seoul
Softer frown lines and a more relaxed expression at Nest Clinic — our women doctors use precisely dosed botulinum toxin, adding fine filler or skin boosters only when lines remain etched at rest.
10 min
injection, same-day return to plans
A
What is the most effective treatment for frown lines between the eyebrows?
Glabellar or frown lines are caused mainly by the corrugator and procerus muscles pulling the brows together. Botulinum toxin such as Xeomin is the standard first treatment: it relaxes these muscles, with softening in 3–7 days and results lasting around 3–4 months. Deep lines that remain at rest may also need a very soft hyaluronic acid filler or skin booster, placed with great care. Results vary between individuals.
- Sessions
- Usually 1, with review at 2 weeks
- Interval
- Every 3–4 months for toxin
- Downtime
- None to minimal — tiny injection marks
- Treatment time
- About 10 minutes
- Onset
- 3–7 days; full effect by 2 weeks
- Results last
- Around 3–4 months for toxin
Understanding glabellar lines
The lines that make you look cross
Glabellar lines are the vertical, sometimes slightly angled creases between the eyebrows, often called the 11 lines. They form when the corrugator and procerus muscles contract as we frown, concentrate or squint, and can remain visible at rest as the skin thins with age.
They can give an angry or tired impression even when you feel relaxed. They are often treated together with forehead lines and crow's feet for a balanced upper face.
Signs you may benefit
- Vertical lines between the brows when frowning
- Lines that stay visible at rest
- People asking if you are tired or upset
- Habitual frowning when reading or in bright light
- Lines deepening over the past few years
Our approach
Relax first, then refine
Most patients need only botulinum toxin; deeper, long-standing lines may need additional care.
Very soft HA filler
Tiny amounts of a fine filler such as Belotero smooth etched lines that remain after the muscles relax — see Belotero.
Skin boosters
Skinvive or Rejuran improve skin quality and fine creasing between the brows.
Combined upper-face plan
Balanced treatment of the frown, forehead and eyes keeps brows in a natural position.
What to expect
A calmer, more relaxed look
Drag the handle to compare. Frown lines soften within days as the muscles relax, giving a more rested expression.
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Before
After 2 wks
Illustration for explanation only — not a patient photograph. Individual results vary; real case photos are shown during your consultation.
Is it right for you?
Good candidates
- Vertical frown lines between the eyebrows
- Early static lines that remain at rest
- First-time toxin patients
- Visitors with only a day or two in Seoul
- People wanting to prevent lines from deepening
Safety first
Possible side effects
Small injection marks, mild redness, bruising and a mild headache are common and short-lived. Uncommon effects include temporary brow asymmetry and, rarely, eyelid drooping (ptosis), which is temporary. We reduce these risks with precise placement and conservative doses.
The area between the brows has delicate blood supply, so filler here carries a higher risk of vascular occlusion. We use filler here only when needed, in very small amounts, with slow low-pressure injection, and keep hyaluronidase available.
Toxin is not given during pregnancy or breastfeeding, or for people with certain neuromuscular conditions such as myasthenia gravis.
Your visit
How treatment works at Nest Clinic
Consultation
Your doctor assesses frown strength and brow position.
Injection map
Points and doses planned for a natural result.
Preparation
Skin cleansed; ice for comfort if needed.
Treatment
Fine-needle injections, about 10 minutes.
Review
Check at 2 weeks, in clinic or by photo.
Medical reviewer · Chief Medical Doctor
Dr. Kyung-yeon Lee
Dr. Lee trained at Seoul National University College of Medicine (M.S.) and completed residency at Seoul National University Hospital. Before joining Nest Clinic she was director at VS Line Clinic in Apgujeong. Nest Clinic is led entirely by women doctors, with one-to-one consultations rather than high-volume treatment.
Seoul National Univ. College of Medicine
Korean Society for Aesthetic Laser Surgery
Korean Academy of Facial Filler
Key Doctor · Jetema e.p.t.q.
This page was medically reviewed by Dr. Kyung-yeon Lee in October 2026. It is for general information and does not replace an in-person diagnosis.
FAQ
Glabellar Lines questions, answered
Does it hurt?
Most patients feel only brief pinches. Ice or numbing cream can be used if you are sensitive.
Will I still be able to frown?
Movement is reduced, not removed entirely, at natural doses. Your expressions remain, but the strong pull that creases the skin softens.
Can I fly home after treatment?
Yes, flying a few hours after treatment is generally fine. Avoid rubbing the area, lying flat or intense exercise for the rest of the day.
How long do results last?
Botulinum toxin usually lasts around 3–4 months. With regular treatment, many patients find lines at rest become less visible over time.
Do I need filler for my frown lines?
Usually not. Filler is considered only for deep lines that remain after toxin, and it is placed with extra caution in this area.
What about other lines on my face?
Shallow lines elsewhere often respond to fine line treatments
such as skin boosters.
Related treatments
Explore upper-face care
Consultation
Soften your frown lines
Send a photo on WhatsApp for a first opinion in English, then book a consultation with our doctors.
Nest Clinic Gangnam · 4F–5F Seocho Building, 453 Gangnam-daero, Seocho-gu, Seoul
Sinnonhyeon Station Exit 7 · Gangnam Station Exit 10
Mon–Fri 10:00–20:00 · Sat 10:00–17:00 · Sun closed
Results differ from person to person. All medical procedures carry potential risks and side effects; a doctor will explain them before treatment. Information on this page is educational and not a substitute for a personal medical consultation.
